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醫學研究趨勢

AI精選本週最具影響力的29個專科論文

最後更新: 2026年5月11日

消化內科5

影響力 2

Gut microbiota-regulated glutathione metabolic rhythms restore obesity-induced colonic inflammatory oscillations.

發表日期: 2026-12-31

Gut microbes

MediLens 收錄日: 2026-05-11

The study investigates the impact of obesity on circadian inflammatory rhythms, a key aspect of metabolic syndrome. It demonstrates that a high-fat diet disrupts microbiota-regulated glutathione metabolism, leading to altered colonic inflammatory rhythms. The use of fructo-oligosaccharide (FOS) a...

在PubMed上閱讀
影響力 2

Endoscopic grading of gastric intestinal metaplasia and microvascular pattern for assessing gastric cancer risk: a prospective study.

發表日期: 2026-12-01

Annals of medicine

MediLens 收錄日: 2026-05-12

This study validates the diagnostic accuracy of the endoscopic grading of gastric intestinal metaplasia (EGGIM) for identifying high-risk gastric intestinal metaplasia (GIM) patients. A total of 144 patients were evaluated, revealing an area under the curve (AUC) of 0.885 for EGGIM in diagnosing ...

在PubMed上閱讀
影響力 3

Significant Intra-pancreatic Fat Deposition as an Independent Prognostic Factor in High-grade Pancreatic Neuroendocrine Neoplasms.

發表日期: 2026-05-11

Annals of surgical oncology

MediLens 收錄日: 2026-05-12

This study evaluates the prognostic value of significant intra-pancreatic fat deposition (IPFD) in patients with high-grade pancreatic neuroendocrine neoplasms (panNENs). Among 87 patients, 27.6% exhibited significant IPFD, which was linked to worse overall and disease-specific survival outcomes....

在PubMed上閱讀
影響力 2

Advanced therapies for extraintestinal manifestations of IBD: a systematic review and meta-analysis.

發表日期: 2026-05-11

Inflammatory bowel diseases

MediLens 收錄日: 2026-05-12

This systematic review evaluated the efficacy of advanced therapies for treating extraintestinal manifestations (EIMs) in inflammatory bowel diseases (IBDs). It included 49 studies, revealing that TNF antagonists and JAK inhibitors were effective for musculoskeletal EIMs, with response rates of 6...

在PubMed上閱讀
影響力 2

Real-world outcomes of pembrolizumab in advanced anal cancer: a nationwide Danish anal Cancer Group report.

發表日期: 2026-05-11

Acta oncologica (Stockholm, Sweden)

MediLens 收錄日: 2026-05-12

This study investigates the effectiveness of pembrolizumab in treating advanced squamous cell carcinoma of the anal canal (SCCA) in a real-world cohort of 37 Danish patients. The objective response rate was 13.5%, with a clinical benefit rate of 48.6%. Median progression-free survival was 4.0 mon...

在PubMed上閱讀

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