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医学研究趋势

AI精选本周最具影响力的29个专科论文

最后更新: 2026年5月22日

风湿免疫科5

影响力 2

Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review).

发表日期: 2026-07-01

Molecular medicine reports

MediLens 收录日: 2026-05-23

This review focuses on the role of the PI3K/AKT signaling pathway in rheumatoid arthritis (RA), highlighting its importance in regulating inflammatory responses, cell survival, and gene expression. It summarizes how PI3K/AKT modulates key genes involved in RA pathogenesis, including cytokines and...

在PubMed上阅读
影响力 1

Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review).

发表日期: 2026-07-01

Molecular medicine reports

MediLens 收录日: 2026-05-23

This review highlights the interrelation between osteoporosis and osteoarthritis, particularly in postmenopausal women, emphasizing estrogen deficiency as a key risk factor. It discusses how estrogen deficiency exacerbates both conditions through mechanisms like chronic inflammation and oxidative...

在PubMed上阅读
影响力 1

NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome.

发表日期: 2026-07-01

Molecular medicine reports

MediLens 收录日: 2026-05-23

This study focuses on the role of the NF‑κB signaling pathway in lacrimal gland injury associated with primary Sjögren's syndrome, particularly its impact on tear secretion in a mouse model.

在PubMed上阅读
影响力 3

Erythrocyte patch for enhanced B cell depletion therapy.

发表日期: 2026-05-22

Science advances

MediLens 收录日: 2026-05-23

The study introduces CD20 EryPatch, a novel therapy that enhances B cell depletion through a dual mechanism involving mechanotransduction and phagocytosis. This living cellular patch adheres to B cells, facilitating effective clearance and demonstrating superior efficacy compared to traditional C...

在PubMed上阅读
影响力 2

Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.

发表日期: 2026-05-22

Medical science monitor : international medical journal of experimental and clinical research

MediLens 收录日: 2026-05-23

This narrative review addresses the management of knee osteoarthritis (KOA), which currently affects over 365 million adults and is projected to increase significantly by 2050. The review critiques conventional practices that focus on end-stage surgical outcomes and advocates for a proactive, int...

在PubMed上阅读

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