AI精选本周最具影响力的29个专科论文
最后更新: 2026年5月11日
发表日期: 2026-12-31
Gut microbes
MediLens 收录日: 2026-05-11
The study investigates the impact of obesity on circadian inflammatory rhythms, a key aspect of metabolic syndrome. It demonstrates that a high-fat diet disrupts microbiota-regulated glutathione metabolism, leading to altered colonic inflammatory rhythms. The use of fructo-oligosaccharide (FOS) a...
在PubMed上阅读发表日期: 2026-12-01
Annals of medicine
MediLens 收录日: 2026-05-12
This study validates the diagnostic accuracy of the endoscopic grading of gastric intestinal metaplasia (EGGIM) for identifying high-risk gastric intestinal metaplasia (GIM) patients. A total of 144 patients were evaluated, revealing an area under the curve (AUC) of 0.885 for EGGIM in diagnosing ...
在PubMed上阅读发表日期: 2026-05-11
Annals of surgical oncology
MediLens 收录日: 2026-05-12
This study evaluates the prognostic value of significant intra-pancreatic fat deposition (IPFD) in patients with high-grade pancreatic neuroendocrine neoplasms (panNENs). Among 87 patients, 27.6% exhibited significant IPFD, which was linked to worse overall and disease-specific survival outcomes....
在PubMed上阅读发表日期: 2026-05-11
Inflammatory bowel diseases
MediLens 收录日: 2026-05-12
This systematic review evaluated the efficacy of advanced therapies for treating extraintestinal manifestations (EIMs) in inflammatory bowel diseases (IBDs). It included 49 studies, revealing that TNF antagonists and JAK inhibitors were effective for musculoskeletal EIMs, with response rates of 6...
在PubMed上阅读发表日期: 2026-05-11
Acta oncologica (Stockholm, Sweden)
MediLens 收录日: 2026-05-12
This study investigates the effectiveness of pembrolizumab in treating advanced squamous cell carcinoma of the anal canal (SCCA) in a real-world cohort of 37 Danish patients. The objective response rate was 13.5%, with a clinical benefit rate of 48.6%. Median progression-free survival was 4.0 mon...
在PubMed上阅读