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AI精选本周最具影响力的29个专科论文

最后更新: 2026年4月1日

消化内科5

影响力 3

Bifunctional nanoparticles based on esterified hydroxypropyl β-cyclodextrin/quaternary ammonium chitosan for ulcerative colitis intervention.

发表日期: 2026-04-01

Food research international (Ottawa, Ont.)

MediLens 收录日: 2026-04-02

This study presents a novel approach to ulcerative colitis therapy using oral nanoparticles that combine anti-inflammatory effects with gut microbiome modulation. The nanoparticles, developed through self-assembly, utilize curcumin for its anti-inflammatory properties and anthocyanin for microbio...

在PubMed上阅读
影响力 3

Exploration of a Model for Elimination of Hepatitis C in Women of Childbearing Age in Primary Hospitals in Southern China.

发表日期: 2026-04-01

Journal of viral hepatitis

MediLens 收录日: 2026-04-02

This study evaluated an intervention model for Hepatitis C virus (HCV) elimination in women of childbearing age, focusing on 'treatment as prevention'. Launched in October 2022, the project enhanced HCV-Ab screening, RNA testing, and treatment referrals through multidisciplinary collaborations. K...

在PubMed上阅读
影响力 3

Graft and Patient Survival After Liver Transplantation for Primary Sclerosing Cholangitis: A French National Cohort Study.

发表日期: 2026-04-01

Liver international : official journal of the International Association for the Study of the Liver

MediLens 收录日: 2026-04-02

This study analyzed outcomes in 571 patients who underwent liver transplantation for primary sclerosing cholangitis (PSC) in France from 1985 to 2019. The median follow-up was 89 months, with patient survival rates at 5, 10, and 20 years being 88.2%, 81.2%, and 62.6%, respectively. Graft survival...

在PubMed上阅读
影响力 3

Novel Silver(I) and Gold(I) N-Heterocyclic Carbene Complexes Induce ROS-Dependent Autophagic Cell Death in Human Hepatoma Cell Line HepG2.

发表日期: 2026-04-01

Chemical biology & drug design

MediLens 收录日: 2026-04-02

This study investigates the cytotoxic effects of sulfonated silver(I) and gold(I) N-heterocyclic carbene complexes on human liver cancer cells. The results indicate that these complexes induce autophagic cell death rather than apoptosis, characterized by increased expression of autophagy markers ...

在PubMed上阅读
影响力 3

Phytogalactolipids triggered oxidative stress to inhibit drug-resistant colorectal cancer by suppressing interferon-α-induced protein 6.

发表日期: 2026-04-01

Phytomedicine : international journal of phytotherapy and phytopharmacology

MediLens 收录日: 2026-04-02

This study investigates the pharmacological mechanism and therapeutic efficacy of galactolipids from Crassocephalum rabens (CRA) for treating drug-resistant colorectal cancer (CRC). CRA demonstrated antitumor activity by inducing ROS-mediated cytotoxicity through the inhibition of IFI6 expression...

在PubMed上阅读

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