종양내과5 편

영향력 2

Baseline FDG PET/CT-Defined Axillary Burden Predicts Axillary Pathologic Complete Response After Neoadjuvant Therapy in Breast Cancer.

발표일: 2026-06-01

Nuklearmedizin. Nuclear medicine

MediLens 수록일: 2026-05-23

This study investigates predictors of axillary pathologic complete response (pCR) after neoadjuvant systemic therapy in clinically node-positive breast cancer. In a retrospective cohort of 115 patients, the rate of axillary pCR was 51.3%. The models developed showed good discrimination with AUC v...

PubMed에서 읽기

영향력 3

Fulvestrant versus capecitabine as maintenance therapy in hormone receptor-positive, HER2-negative metastatic breast cancer after first-line chemotherapy (FAMILY): a multicenter, open-label, randomized, phase 3 trial.

발표일: 2026-05-22

Signal transduction and targeted therapy

MediLens 수록일: 2026-05-23

This study evaluates the efficacy and safety of fulvestrant versus capecitabine as maintenance therapy in hormone receptor-positive, HER-2 negative metastatic breast cancer patients after first-line chemotherapy. The trial involved 210 patients and found that fulvestrant significantly improved me...

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영향력 3

Aptamer Nanoswitch-Mediated Lock-Expose Mechanism Enables Highly Sensitive In Vitro Detection and Precise In Situ Membrane Imaging of HER2 Protein.

발표일: 2026-05-22

ACS sensors

MediLens 수록일: 2026-05-23

This study presents a novel HER2-specific aptamer nanoswitch for the sensitive detection of HER2 expression in breast cancer. The sensor demonstrated a linear detection range from 10 fg/mL to 10 ng/mL and a limit of detection of 1.42 fg/mL. It successfully distinguished between healthy individual...

PubMed에서 읽기

영향력 3

Wash-Free Digital Detection of Tumor Extracellular Vesicles via Plasmonic Droplet Microfluidics.

발표일: 2026-05-22

ACS sensors

MediLens 수록일: 2026-05-23

PlasDroplex is a novel wash-free digital plasmonic assay designed for the early detection of tumor-derived extracellular vesicles (EVs) in cancer diagnostics. This method allows for the detection of EVs without the need for washing or multistep labeling, utilizing a coencapsulation of plasma with...

PubMed에서 읽기

영향력 3

Urine-Based Noninvasive Detection of Prostate Cancer Using Human Olfactory Receptor-Embedded Nanodiscs.

발표일: 2026-05-22

ACS sensors

MediLens 수록일: 2026-05-23

This study presents a novel urine-based diagnostic platform for prostate cancer that utilizes a sensor array embedded with human olfactory receptors, combined with fluorescence sensing and machine learning. The platform aims to improve specificity in diagnosing prostate cancer, addressing the lim...

PubMed에서 읽기

의학 연구 트렌드

종양내과5 편

Baseline FDG PET/CT-Defined Axillary Burden Predicts Axillary Pathologic Complete Response After Neoadjuvant Therapy in Breast Cancer.

Fulvestrant versus capecitabine as maintenance therapy in hormone receptor-positive, HER2-negative metastatic breast cancer after first-line chemotherapy (FAMILY): a multicenter, open-label, randomized, phase 3 trial.

Aptamer Nanoswitch-Mediated Lock-Expose Mechanism Enables Highly Sensitive In Vitro Detection and Precise In Situ Membrane Imaging of HER2 Protein.

Wash-Free Digital Detection of Tumor Extracellular Vesicles via Plasmonic Droplet Microfluidics.

Urine-Based Noninvasive Detection of Prostate Cancer Using Human Olfactory Receptor-Embedded Nanodiscs.

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