Metabolic memory in the kidney: how lactate and lactylation drive the path from acute injury to chronic disease.
발표일: 2026-12-01
Renal failure
MediLens 수록일: 2026-05-22
This review discusses the role of lactate and lysine lactylation in the progression from acute kidney injury to chronic kidney disease. It identifies four maladaptive repair processes involved: mitochondrial dysfunction, metabolic reprogramming, inflammation, and fibrosis. Lactylation is emphasiz...
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