의학 연구 트렌드

AI가 선별한 이번 주 29개 전문과의 주요 논문

마지막 업데이트: 2026년 4월 1일

심장내과5

영향력 3

Evolving Strategies in Cardiac Amyloidosis: From Mechanistic Discoveries to Diagnostic and Therapeutic Advances.

발표일: 2026-04-01

Heart failure clinics

MediLens 수록일: 2026-04-02

The diagnosis and treatment of cardiac amyloidosis have significantly progressed over the last decade, focusing on the pathogenesis of the disease. Noninvasive imaging has enhanced the diagnosis of ATTR cardiomyopathy, while novel treatments, including protein stabilizers and gene editing, have e...

PubMed에서 읽기
영향력 3

Surgical Site Infection in Coronary Artery Bypass: Observational Study.

발표일: 2026-04-01

International journal of nursing practice

MediLens 수록일: 2026-04-02

This observational study assessed adherence to surgical site infection prevention measures in patients undergoing coronary artery bypass grafting at a university hospital. The mean adherence score was 71.18%, but the infection rate was notably high at 55.8%, with some infections leading to hospit...

PubMed에서 읽기
영향력 3

Bundled Care Interventions for the Management of Intracerebral Hemorrhage: A Review.

발표일: 2026-04-01

Critical care nurse

MediLens 수록일: 2026-04-02

The management of spontaneous intracerebral hemorrhage is critical due to its significant impact on disability and mortality. The 2024 American Heart Association/American Stroke Association guidelines recommend bundled care interventions, including blood pressure control and anticoagulation rever...

PubMed에서 읽기
영향력 3

Association of insomnia and its proteomic signatures with incident heart failure: A European population-based study.

발표일: 2026-04-01

Sleep health

MediLens 수록일: 2026-04-02

This study investigates the association between insomnia and heart failure using data from 52,273 participants in the UK Biobank. It finds that insomnia is independently linked to an increased risk of heart failure (HR: 1.39; 95% CI: 1.17-1.65) and identifies 118 proteins related to insomnia that...

PubMed에서 읽기
영향력 2

Decreased AMP-kinase function in pulmonary artery smooth muscle cells contributes to pulmonary artery remodeling in persistent pulmonary hypertension of the newborn.

발표일: 2026-04-01

American journal of physiology. Lung cellular and molecular physiology

MediLens 수록일: 2026-04-02

This study investigates the role of decreased AMPK function in pulmonary artery smooth muscle cells (PASMCs) in the context of persistent pulmonary hypertension of the newborn (PPHN). Using fetal lambs, the research reveals that PPHN is associated with decreased levels of phosphorylated AMPK, PGC...

PubMed에서 읽기

종양내과1

영향력 1

Bridging mechanism and clinic: unlocking the full potential of oncolytic virus-based immunotherapy.

발표일: 2026-03-31

Molecular cancer

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기

신경과1

영향력 1

Retraction Note: An intelligent learning system based on electronic health records for unbiased stroke prediction.

발표일: 2026-03-31

Scientific reports

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기

소화기내과5

영향력 3

Bifunctional nanoparticles based on esterified hydroxypropyl β-cyclodextrin/quaternary ammonium chitosan for ulcerative colitis intervention.

발표일: 2026-04-01

Food research international (Ottawa, Ont.)

MediLens 수록일: 2026-04-02

This study presents a novel approach to ulcerative colitis therapy using oral nanoparticles that combine anti-inflammatory effects with gut microbiome modulation. The nanoparticles, developed through self-assembly, utilize curcumin for its anti-inflammatory properties and anthocyanin for microbio...

PubMed에서 읽기
영향력 3

Exploration of a Model for Elimination of Hepatitis C in Women of Childbearing Age in Primary Hospitals in Southern China.

발표일: 2026-04-01

Journal of viral hepatitis

MediLens 수록일: 2026-04-02

This study evaluated an intervention model for Hepatitis C virus (HCV) elimination in women of childbearing age, focusing on 'treatment as prevention'. Launched in October 2022, the project enhanced HCV-Ab screening, RNA testing, and treatment referrals through multidisciplinary collaborations. K...

PubMed에서 읽기
영향력 3

Graft and Patient Survival After Liver Transplantation for Primary Sclerosing Cholangitis: A French National Cohort Study.

발표일: 2026-04-01

Liver international : official journal of the International Association for the Study of the Liver

MediLens 수록일: 2026-04-02

This study analyzed outcomes in 571 patients who underwent liver transplantation for primary sclerosing cholangitis (PSC) in France from 1985 to 2019. The median follow-up was 89 months, with patient survival rates at 5, 10, and 20 years being 88.2%, 81.2%, and 62.6%, respectively. Graft survival...

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영향력 3

Novel Silver(I) and Gold(I) N-Heterocyclic Carbene Complexes Induce ROS-Dependent Autophagic Cell Death in Human Hepatoma Cell Line HepG2.

발표일: 2026-04-01

Chemical biology & drug design

MediLens 수록일: 2026-04-02

This study investigates the cytotoxic effects of sulfonated silver(I) and gold(I) N-heterocyclic carbene complexes on human liver cancer cells. The results indicate that these complexes induce autophagic cell death rather than apoptosis, characterized by increased expression of autophagy markers ...

PubMed에서 읽기
영향력 3

Phytogalactolipids triggered oxidative stress to inhibit drug-resistant colorectal cancer by suppressing interferon-α-induced protein 6.

발표일: 2026-04-01

Phytomedicine : international journal of phytotherapy and phytopharmacology

MediLens 수록일: 2026-04-02

This study investigates the pharmacological mechanism and therapeutic efficacy of galactolipids from Crassocephalum rabens (CRA) for treating drug-resistant colorectal cancer (CRC). CRA demonstrated antitumor activity by inducing ROS-mediated cytotoxicity through the inhibition of IFI6 expression...

PubMed에서 읽기

호흡기내과5

영향력 3

Upfront treatment with osimertinib in lung cancer patients with and without active brain metastases, and the role of ctDNA as a biomarker; a phase II clinical trial (the FIOL study).

발표일: 2026-04-01

Lung cancer (Amsterdam, Netherlands)

MediLens 수록일: 2026-04-02

This phase II trial evaluated the efficacy of osimertinib in patients with EGFR-mutated non-small cell lung cancer, focusing on those with untreated brain metastases. The study included 100 patients, showing an overall objective response rate of 72.0%, with 81.8% in those with measurable brain me...

PubMed에서 읽기
영향력 3

Overall survival for amivantamab plus lazertinib versus osimertinib as first-line treatment in Asian participants with EGFR-mutant advanced NSCLC: A MARIPOSA subset analysis.

발표일: 2026-04-01

Lung cancer (Amsterdam, Netherlands)

MediLens 수록일: 2026-04-02

The study evaluated the overall survival (OS) of amivantamab-lazertinib compared to osimertinib in Asian patients with untreated EGFR-mutated advanced non-small cell lung cancer (NSCLC). Results showed a significant improvement in OS for amivantamab-lazertinib, with a hazard ratio of 0.74 at a me...

PubMed에서 읽기
영향력 3

Defining response-adapted surgery after neoadjuvant systemic therapy in sinonasal squamous cell carcinoma.

발표일: 2026-04-01

Oral oncology

MediLens 수록일: 2026-04-02

This study presents a novel classification system for documenting surgical outcomes in patients with sinonasal squamous cell carcinoma (SCC) undergoing neoadjuvant therapy. The framework addresses the complexities of sinonasal anatomy and aims to standardize the evaluation of surgical morbidity a...

PubMed에서 읽기
영향력 3

Xbp1-driven lipid metabolism promotes immunosuppression in lung cancer: Jianpi Chutan Jiedu formula reshapes metabolic-immune crosstalk.

발표일: 2026-04-01

Phytomedicine : international journal of phytotherapy and phytopharmacology

MediLens 수록일: 2026-04-02

This study investigates the antitumor efficacy of the Jianpi Chutan Jiedu Formula (JCJ) in lung cancer (LC) and its underlying mechanisms. It identifies high expression of XBP1 in LC and demonstrates that Xbp1 overexpression leads to lipid accumulation and immunosuppression in the tumor microenvi...

PubMed에서 읽기
영향력 3

Pediatric Invasive Group A Streptococcus Infections with Central Nervous System Involvement: A Single Institution Case Series in Southern New England.

발표일: 2026-04-01

Rhode Island medical journal (2013)

MediLens 수록일: 2026-04-02

This case series highlights three rare pediatric cases of invasive Group A Streptococcus (iGAS) infections with central nervous system involvement, all occurring within a two-month period in Massachusetts. The patients presented with severe conditions, including meningitis and subdural collection...

PubMed에서 읽기

내분비내과5

영향력 3

Development and Validation of Prognostic Models in Patients With Stage IV Thyroid Cancer Undergoing Surgical Treatment.

발표일: 2026-04-01

The American surgeon

MediLens 수록일: 2026-04-02

This study addresses the low survival rates in advanced thyroid cancer by developing a prognostic prediction model based on a cohort of 670 patients from the SEER database. Using univariate and multivariate Cox regression analyses, significant independent risk factors were identified, including g...

PubMed에서 읽기
영향력 3

Clinical stage IIA/B embryonal carcinoma predominant nonseminomatous germ cell tumor: Minimizing treatment burden.

발표일: 2026-04-01

Urologic oncology

MediLens 수록일: 2026-04-02

This study investigates the treatment burden of primary retroperitoneal lymph node dissection (RPLND) versus chemotherapy in patients with embryonal carcinoma predominance in nonseminomatous germ cell tumors. Among 126 patients, primary RPLND achieved a 3-year recurrence-free survival of 85.1%, w...

PubMed에서 읽기
영향력 3

Immunotherapy response in microsatellite-stable poorly differentiated thyroid carcinoma with mismatch repair deficiency and high tumor mutational burden.

발표일: 2026-04-01

Archives of endocrinology and metabolism

MediLens 수록일: 2026-04-02

This case report discusses a 71-year-old woman with poorly differentiated thyroid carcinoma (PDTC) who was ineligible for standard treatments. Molecular profiling indicated a high tumor mutational burden (TMB) and specific somatic mutations. The patient was treated with pembrolizumab, resulting i...

PubMed에서 읽기
영향력 3

NR3C1 Modulates Wnt Signalling to Influence the Invasiveness and Immune Features of Nonfunctioning Invasive Pituitary Adenomas.

발표일: 2026-04-01

Journal of cellular and molecular medicine

MediLens 수록일: 2026-04-02

This study investigates the role of NR3C1 in the invasiveness of nonfunctioning invasive pituitary adenomas (NIPAs). Using RNA-seq and mass spectrometry, the researchers identified NR3C1 as significantly upregulated in NIPAs, with strong discriminatory power in ROC analysis. Functional experiment...

PubMed에서 읽기
영향력 3

USP20-RAB8A signaling axis restricts pancreatic cancer progression by disrupting GLUT1 vesicular trafficking and inhibiting glucose uptake.

발표일: 2026-04-01

Cancer letters

MediLens 수록일: 2026-04-02

This study identifies a novel mechanism regulating glucose transporter 1 (GLUT1) in pancreatic ductal adenocarcinoma (PDAC) cells through RAB8A-dependent vesicular trafficking. RAB8A enhances GLUT1 localization to the membrane, increasing glucose uptake, while ubiquitin-specific peptidase 20 (USP...

PubMed에서 읽기

신장내과5

영향력 3

Elevated triglyceride-glucose index is associated with increased risk of chronic kidney disease and end-stage renal disease in type 1 diabetes: Nationwide cohort study.

발표일: 2026-04-01

Diabetes, obesity & metabolism

MediLens 수록일: 2026-04-02

This study investigates the association between the triglyceride-glucose (TyG) index and long-term renal outcomes in a nationwide cohort of 14,782 adults with type 1 diabetes. The findings reveal a significant dose-response relationship, with individuals in the highest quartile of the TyG index h...

PubMed에서 읽기
영향력 3

Ceftriaxone administration reduces vascular calcification associated with experimental models of chronic kidney disease.

발표일: 2026-04-01

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

MediLens 수록일: 2026-04-02

This study investigates the effects of gut microbiota depletion on chronic kidney disease (CKD) and vascular calcification (VC) using Wistar rats. The research demonstrates that antibiotic treatment with ceftriaxone significantly lowers serum phosphate levels, reduces uremic toxins, and decreases...

PubMed에서 읽기
영향력 3

Node Positive Resected Renal Cell Carcinoma Portends a Poor Prognosis: Results From the Canadian Kidney Cancer Collaboration.

발표일: 2026-04-01

Clinical genitourinary cancer

MediLens 수록일: 2026-04-02

This study investigates the recurrence and survival patterns in patients with pathologically node-positive, nonmetastatic renal cell carcinoma (RCC). A total of 113 patients were analyzed, revealing a 77% recurrence rate at a median of 4.8 months, primarily with distant metastases. The median can...

PubMed에서 읽기
영향력 2

Quality of Life After Abdominal Wall Reconstruction and the Establishment of a Pathway for Renal Transplant Recipients.

발표일: 2026-04-01

Transplantation proceedings

MediLens 수록일: 2026-04-02

This study evaluates the outcomes and quality of life (QoL) impact for renal transplant recipients undergoing abdominal wall reconstruction (AWR) for incisional hernia repair. A total of 34 patients were included, with 26 eligible for the QoL survey, and 17 responses received. Complications occur...

PubMed에서 읽기
영향력 2

Minimizing radiation exposure in pediatric nephrolithiasis: The effectiveness of a low-dose computed tomography protocol.

발표일: 2026-04-01

Journal of pediatric urology

MediLens 수록일: 2026-04-02

This study reports the development and implementation of a low-dose computed tomography protocol for pediatric nephrolithiasis, aiming to reduce radiation exposure. The protocol demonstrated a significant reduction in radiation dose compared to standard protocols while maintaining diagnostic accu...

PubMed에서 읽기

류마티스내과3

영향력 2

Incidence of Surgery for Pediatric Wrist Ganglion Cysts.

발표일: 2026-04-01

Hand (New York, N.Y.)

MediLens 수록일: 2026-04-02

This study provides a nationwide analysis of pediatric ganglion cysts, highlighting the increasing incidence and surgical management trends with age. A total of 33,884 patients were identified, showing that older patients and females were more likely to undergo surgery. The study emphasizes the i...

PubMed에서 읽기
영향력 1

Certolizumab pegol, abatacept, tocilizumab or active conventional therapy in early rheumatoid arthritis: 48-week patient-reported outcomes from the NORD-STAR trial.

발표일: 2026-04-01

The Lancet. Rheumatology

MediLens 수록일: 2026-04-02

(Summary generation failed. Please refer to the original article.)

PubMed에서 읽기
영향력 1

Outcomes and Complications of Suture-Button versus All-Suture Suspensionplasty in Thumb Carpometacarpal Arthritis: A Retrospective Comparative Study.

발표일: 2026-04-01

The journal of hand surgery Asian-Pacific volume

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기

감염내과1

영향력 1

An Unusual Cause of Massive Gastrointestinal Bleed in a Girl with Abdominal Tuberculosis.

발표일: 2026-03-31

Indian pediatrics

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기

혈액내과5

영향력 1

Bronchiolitis Obliterans or Busulfan-Induced Lung Injury? A Pediatric Case of Hematopoietic Stem Cell Transplantation.

발표일: 2026-04-01

Pediatric pulmonology

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Eosinophilic, polymorphic, and pruritic eruption associated with radiation treated with dupilumab in a patient with Hodgkin lymphoma.

발표일: 2026-04-01

JAAD case reports

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Bridging therapy before CAR-T for multiple myeloma: a survey from the CMWP and CTIWP of the EBMT.

발표일: 2026-03-31

Bone marrow transplantation

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Successful Outcome of Haploidentical Hematopoietic Stem Cell Transplantation in X-Linked Sideroblastic Anemia.

발표일: 2026-03-31

Pediatric blood & cancer

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

HSR26-237: Meta-Analysis Confirms Venetoclax Plus Decitabine as a Frontline Game-Changer in Elderly AML (Acute Myeloid Leukemia).

발표일: 2026-03-31

Journal of the National Comprehensive Cancer Network : JNCCN

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기

정신건강의학과1

영향력 1

Correction to "Clinical and Societal Burden of Incident Major Depressive Disorder: A Population-Wide Cohort Study in Stockholm".

발표일: 2026-04-01

Acta psychiatrica Scandinavica

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기

피부과5

영향력 1

On the role of cholesterol, vitamin D, lumisterol, and tachysterol signaling in psoriasis.

발표일: 2026-04-01

The Journal of investigative dermatology

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Successful use of spesolimab in refractory pyoderma gangrenosum.

발표일: 2026-04-01

JAAD case reports

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Response to Brenaut et al., "Response to Pham et al's 'Sensory symptoms of scalp psoriasis are not sensitive scalp syndrome'".

발표일: 2026-04-01

JAAD international

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Adults with a history of melanoma have higher odds of laryngeal cancer in the United States.

발표일: 2026-04-01

JAAD international

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Folate-functionalized core-shell nanocarrier System for sustained and targeted delivery of

발표일: 2026-04-01

Drug development and industrial pharmacy

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기

안과3

영향력 1

Association between PCSK9 inhibitor use and risk of age-related macular degeneration.

발표일: 2026-04-01

Eye (London, England)

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Comment on: CATALYZE: a deep learning approach for cataract assessment and grading on SS-OCT images.

발표일: 2026-04-01

Journal of cataract and refractive surgery

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Comment on: ``Development and Evaluation of an Artificial Intelligence Model to Set Target IOP for Glaucoma''.

발표일: 2026-04-01

American journal of ophthalmology

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기

소아청소년과2

영향력 1

Evaluation of PCORnet as an Approach to Accessing Electronic Health Record (EHR) Data for Cleft Outcomes Research: Advantages and Limitations.

발표일: 2026-04-01

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Toxic epidermal necrolysis in a preschooler associated with adenovirus respiratory infection: A case report.

발표일: 2026-04-01

JAAD case reports

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기

응급의학과3

영향력 1

Intravenous Access Should Be Prioritized Over Intraosseous Access in Cardiac Arrest.

발표일: 2026-04-01

Annals of emergency medicine

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

"Perioperative use of factor concentrates and blood products: a survey of clinical practices in the United States: communication from the ISTH Subcommittee on Perioperative and Critical Care": comment from Erdoes et al.

발표일: 2026-04-01

Journal of thrombosis and haemostasis : JTH

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Ketamine Versus Etomidate in Rapid Sequence Intubation: What Difference Would Convince You?: April 2026 Annals of Emergency Medicine Journal Club.

발표일: 2026-04-01

Annals of emergency medicine

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기

외과5

영향력 1

Intrapericardial congenital diaphragmatic hernia: three-dimensional reconstruction.

발표일: 2026-04-01

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Displaced kidneys in a giant inguinoscrotal hernia: an unusual cause of hydronephrosis.

발표일: 2026-04-01

Kidney international

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Local infiltration of liposomal bupivacaine is associated with reduced postoperative admission in anterior abdominal hernia repair.

발표일: 2026-04-01

Surgery

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Incisional hernia repair using component separation with perforator preservation and onlay mesh: A pilot study.

발표일: 2026-03-31

Hernia : the journal of hernias and abdominal wall surgery

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Effect of mesh plane on short-term surgical and functional outcomes in ventral hernia repair with associated rectus diastasis.

발표일: 2026-03-31

Hernia : the journal of hernias and abdominal wall surgery

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기

산부인과5

영향력 1

How She Was Born.

발표일: 2026-04-01

Annals of surgery

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Enhancing diversity in endometriosis clinical trials: Application of the clinical diversity scoring framework.

발표일: 2026-04-01

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Robotic-assisted transumbilical single-site and transvaginal NOTES resection of abdominal wall cesarean scar endometriosis: Two case reports.

발표일: 2026-04-01

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Prenatal Diagnosis of Spinal Muscular Atrophy Facilitates Ultrarapid Treatment After Birth.

발표일: 2026-04-01

Pediatric neurology

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기
영향력 1

Polypoid Endometriosis Mimicking Peritoneal Carcinomatosis.

발표일: 2026-04-01

Journal of minimally invasive gynecology

MediLens 수록일: 2026-04-02

(No abstract provided)

PubMed에서 읽기

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