Nefrologia5 articoli

Impatto 3

Impact of pre-operative factors on post-operative atrial fibrillation outcomes after cardiac surgery: systematic review with meta-analysis, trial sequential analysis, and meta-regression.

Pubblicato: 2026-05-11

Acta cardiologica

MediLens Indicizzato: 2026-05-12

This systematic review and meta-analysis evaluated the association between post-operative atrial fibrillation (POAF) and adverse outcomes in cardiac surgery patients. Analyzing 54 studies involving 623,962 patients, the findings revealed that POAF significantly increases the risk of early mortali...

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Impatto 3

Beyond binary AKI classification: development and external validation of a distributional model predicting serum creatinine and urine output trajectories in ICU patients.

Pubblicato: 2026-05-10

Critical care (London, England)

MediLens Indicizzato: 2026-05-12

This study presents a novel multi-step, multivariate distributional regression model for predicting acute kidney injury (AKI) in ICU patients. Developed from a training cohort of 4,118 ICU stays, the model was externally validated across four diverse cohorts, demonstrating a mean AUC-PR of 0.774,...

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Impatto 2

Chrysin attenuates tramadol-driven renal dysfunction via regulation of RNA networks, antioxidant pathways, and ketogenic metabolism.

Pubblicato: 2026-05-10

European journal of pharmacology

MediLens Indicizzato: 2026-05-11

This study investigates the nephrotoxic effects of tramadol on renal function and the potential protective role of chrysin. The results show that tramadol significantly increases serum creatinine and BUN levels, as well as various renal damage biomarkers. Additionally, there are notable increases...

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Impatto 1

Clinical Prediction Models for Acute Kidney Injury in Neonatology-A Systematic Review and Modelling Analysis.

Pubblicato: 2026-05-10

Journal of paediatrics and child health

MediLens Indicizzato: 2026-05-12

This study reviews clinical prediction rules (CPRs) for predicting acute kidney injury (AKI) in neonates within neonatal intensive care units (NICUs). A systematic search identified 685 articles, with three meeting inclusion criteria after full-text review. The sample sizes of these studies range...

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Impatto 3

Transition from acute kidney injury to chronic kidney disease: molecular mechanisms and therapeutic interventions.

Pubblicato: 2026-05-09

Molecular biomedicine

MediLens Indicizzato: 2026-05-11

This study emphasizes the role of acute kidney injury (AKI) as a significant contributor to chronic kidney disease (CKD) progression, highlighting the mechanisms involved, such as inadequate repair and persistent structural damage. It discusses the pathological processes, including cell cycle arr...

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Tendenze della Ricerca Medica

Nefrologia5 articoli

Impact of pre-operative factors on post-operative atrial fibrillation outcomes after cardiac surgery: systematic review with meta-analysis, trial sequential analysis, and meta-regression.

Beyond binary AKI classification: development and external validation of a distributional model predicting serum creatinine and urine output trajectories in ICU patients.

Chrysin attenuates tramadol-driven renal dysfunction via regulation of RNA networks, antioxidant pathways, and ketogenic metabolism.

Clinical Prediction Models for Acute Kidney Injury in Neonatology-A Systematic Review and Modelling Analysis.

Transition from acute kidney injury to chronic kidney disease: molecular mechanisms and therapeutic interventions.

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