Tendenze della Ricerca Medica

Le pubblicazioni più impattanti della settimana in 29 specialità, curate dall'IA

Ultimo aggiornamento: 22 mag 2026

Cardiologia5 articoli

Impatto 1

Statement of Retraction: Long non-coding RNA lincRNA-erythroid prosurvival attenuates inflammation by enhancing myosin heavy chain 6 stability through recruitment of heterogeneous nuclear ribonucleoprotein L in myocardial infarction.

Pubblicato: 2026-12-01

Bioengineered

MediLens Indicizzato: 2026-05-23

(No abstract provided)

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Impatto 2

Dynamic regulation of the 'mitochondria‑immune axis' in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review).

Pubblicato: 2026-07-01

Molecular medicine reports

MediLens Indicizzato: 2026-05-23

Myocardial infarction (MI) involves not only cardiomyocyte necrosis but also immune system activation and mitochondrial energy metabolism issues. Mitochondrial damage leads to impaired ATP production and excess release of metabolites, promoting M1 macrophage polarization and secondary myocardial ...

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Impatto 2

Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review).

Pubblicato: 2026-07-01

Molecular medicine reports

MediLens Indicizzato: 2026-05-23

This review discusses the role of lipophagy in atherosclerosis (AS), highlighting its importance in lipid homeostasis and plaque stabilization. It summarizes key regulatory networks and the effects of lipophagy on various cell types involved in AS, including macrophages, vascular smooth muscle ce...

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Impatto 3

SREBP1 Transactivation of NHE3 Impairs Cardiac Contraction and Aggravates Heart Failure.

Pubblicato: 2026-05-22

Circulation

MediLens Indicizzato: 2026-05-23

This study investigates the role of SREBP1 in heart failure with reduced ejection fraction (HFrEF), highlighting its activation in human and mouse hearts. The findings reveal that SREBP1 contributes to impaired cardiac contractility and dysregulated calcium handling through the transactivation of...

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Impatto 2

Drug-Induced Noninfectious Myocarditis/Pericarditis: A Real-World Pharmacovigilance Study Using the FAERS Database.

Pubblicato: 2026-05-22

Cardiovascular toxicology

MediLens Indicizzato: 2026-05-23

This study identifies drugs associated with drug-induced noninfectious myocarditis/pericarditis by analyzing 21,422 adverse event reports from the FDA database. A total of 953 drugs were suspected, with clozapine, nivolumab, and pembrolizumab being the most frequently reported. The study highligh...

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