Hematología5 artículos

Impacto 2

Economic burden associated with switching from frontline pegaspargase or calaspargase pegol to second-line recombinant

Publicado: 2026-12-01

Journal of medical economics

MediLens Indexado: 2026-05-23

This retrospective study assessed the costs and healthcare resource utilization associated with switching from frontline pegaspargase/cal-aspargase pegol to second-line recombinant asparaginase in pediatric and AYA patients with acute lymphoblastic leukemia (ALL). A total of 154 patients were ide...

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Impacto 2

Hungry bone syndrome-like state following denosumab in a patient with multiple myeloma.

Publicado: 2026-07-01

JCEM case reports

MediLens Indexado: 2026-05-23

This case study presents a 76-year-old man with newly diagnosed multiple myeloma who experienced severe, prolonged hypocalcemia following denosumab treatment. The patient had elevated creatinine and calcium levels prior to treatment, and developed significant mineral imbalances despite aggressive...

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Impacto 3

Hypophosphatemia as a Marker for Immune Effector Cell-Associated Neurotoxicity Syndrome in Chimeric Antigen Receptor T Cell Recipients.

Publicado: 2026-05-22

Hematology/oncology and stem cell therapy

MediLens Indexado: 2026-05-23

Hypophosphatemia is prevalent in patients undergoing CAR-T therapy, occurring in 71.5% of recipients. The condition is linked to an increased risk of immune effector cell-associated neurotoxicity syndrome (ICANS), with a hazard ratio of 2.87. Notably, hypophosphatemia typically precedes ICANS by ...

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Impacto 2

Haploidentical donor versus double-unit cord blood transplantation in hematologic malignancies: comparative survival and graft-versus-host disease outcomes from a decade of real-world experience.

Publicado: 2026-05-22

BMC cancer

MediLens Indexado: 2026-05-23

This study compares haploidentical donor (HID) and double-unit umbilical cord blood (DUCB) transplantation in 97 patients with hematologic malignancies. HID recipients had faster neutrophil and platelet recovery and lower rates of grade II-IV acute GVHD compared to DUCB recipients. However, overa...

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Impacto 2

The Two-Step Allogeneic Stem Cell Transplant Is Associated with Excellent Engraftment, Improved Survival and Low Nonrelapse Mortality in Patients with Myelofibrosis.

Publicado: 2026-05-22

Hematology/oncology and stem cell therapy

MediLens Indexado: 2026-05-23

This study evaluates the outcomes of 32 myelofibrosis patients who underwent allogeneic hematopoietic stem cell transplantation (HSCT) using a two-step transplant approach. The approach resulted in favorable 1-year and 5-year overall survival rates of 83% and 68%, respectively, and reduced nonrel...

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Tendencias en Investigación Médica

Hematología5 artículos

Economic burden associated with switching from frontline pegaspargase or calaspargase pegol to second-line recombinant

Hungry bone syndrome-like state following denosumab in a patient with multiple myeloma.

Hypophosphatemia as a Marker for Immune Effector Cell-Associated Neurotoxicity Syndrome in Chimeric Antigen Receptor T Cell Recipients.

Haploidentical donor versus double-unit cord blood transplantation in hematologic malignancies: comparative survival and graft-versus-host disease outcomes from a decade of real-world experience.

The Two-Step Allogeneic Stem Cell Transplant Is Associated with Excellent Engraftment, Improved Survival and Low Nonrelapse Mortality in Patients with Myelofibrosis.

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