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Tendencias en Investigación Médica

Las publicaciones de mayor impacto de la semana en 29 especialidades, seleccionadas por IA

Última actualización: 1 abr 2026

Gastroenterología5 artículos

Impacto 3

Bifunctional nanoparticles based on esterified hydroxypropyl β-cyclodextrin/quaternary ammonium chitosan for ulcerative colitis intervention.

Publicado: 2026-04-01

Food research international (Ottawa, Ont.)

MediLens Indexado: 2026-04-02

This study presents a novel approach to ulcerative colitis therapy using oral nanoparticles that combine anti-inflammatory effects with gut microbiome modulation. The nanoparticles, developed through self-assembly, utilize curcumin for its anti-inflammatory properties and anthocyanin for microbio...

Leer en PubMed
Impacto 3

Exploration of a Model for Elimination of Hepatitis C in Women of Childbearing Age in Primary Hospitals in Southern China.

Publicado: 2026-04-01

Journal of viral hepatitis

MediLens Indexado: 2026-04-02

This study evaluated an intervention model for Hepatitis C virus (HCV) elimination in women of childbearing age, focusing on 'treatment as prevention'. Launched in October 2022, the project enhanced HCV-Ab screening, RNA testing, and treatment referrals through multidisciplinary collaborations. K...

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Impacto 3

Graft and Patient Survival After Liver Transplantation for Primary Sclerosing Cholangitis: A French National Cohort Study.

Publicado: 2026-04-01

Liver international : official journal of the International Association for the Study of the Liver

MediLens Indexado: 2026-04-02

This study analyzed outcomes in 571 patients who underwent liver transplantation for primary sclerosing cholangitis (PSC) in France from 1985 to 2019. The median follow-up was 89 months, with patient survival rates at 5, 10, and 20 years being 88.2%, 81.2%, and 62.6%, respectively. Graft survival...

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Impacto 3

Novel Silver(I) and Gold(I) N-Heterocyclic Carbene Complexes Induce ROS-Dependent Autophagic Cell Death in Human Hepatoma Cell Line HepG2.

Publicado: 2026-04-01

Chemical biology & drug design

MediLens Indexado: 2026-04-02

This study investigates the cytotoxic effects of sulfonated silver(I) and gold(I) N-heterocyclic carbene complexes on human liver cancer cells. The results indicate that these complexes induce autophagic cell death rather than apoptosis, characterized by increased expression of autophagy markers ...

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Impacto 3

Phytogalactolipids triggered oxidative stress to inhibit drug-resistant colorectal cancer by suppressing interferon-α-induced protein 6.

Publicado: 2026-04-01

Phytomedicine : international journal of phytotherapy and phytopharmacology

MediLens Indexado: 2026-04-02

This study investigates the pharmacological mechanism and therapeutic efficacy of galactolipids from Crassocephalum rabens (CRA) for treating drug-resistant colorectal cancer (CRC). CRA demonstrated antitumor activity by inducing ROS-mediated cytotoxicity through the inhibition of IFI6 expression...

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