Rheumatologie5 Artikel

Impact 2

Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review).

Veröffentlicht: 2026-07-01

Molecular medicine reports

MediLens Indexiert: 2026-05-23

This review focuses on the role of the PI3K/AKT signaling pathway in rheumatoid arthritis (RA), highlighting its importance in regulating inflammatory responses, cell survival, and gene expression. It summarizes how PI3K/AKT modulates key genes involved in RA pathogenesis, including cytokines and...

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Impact 1

Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review).

Veröffentlicht: 2026-07-01

Molecular medicine reports

MediLens Indexiert: 2026-05-23

This review highlights the interrelation between osteoporosis and osteoarthritis, particularly in postmenopausal women, emphasizing estrogen deficiency as a key risk factor. It discusses how estrogen deficiency exacerbates both conditions through mechanisms like chronic inflammation and oxidative...

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Impact 1

NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome.

Veröffentlicht: 2026-07-01

Molecular medicine reports

MediLens Indexiert: 2026-05-23

This study focuses on the role of the NF‑κB signaling pathway in lacrimal gland injury associated with primary Sjögren's syndrome, particularly its impact on tear secretion in a mouse model.

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Impact 3

Erythrocyte patch for enhanced B cell depletion therapy.

Veröffentlicht: 2026-05-22

Science advances

MediLens Indexiert: 2026-05-23

The study introduces CD20 EryPatch, a novel therapy that enhances B cell depletion through a dual mechanism involving mechanotransduction and phagocytosis. This living cellular patch adheres to B cells, facilitating effective clearance and demonstrating superior efficacy compared to traditional C...

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Impact 2

Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.

Veröffentlicht: 2026-05-22

Medical science monitor : international medical journal of experimental and clinical research

MediLens Indexiert: 2026-05-23

This narrative review addresses the management of knee osteoarthritis (KOA), which currently affects over 365 million adults and is projected to increase significantly by 2050. The review critiques conventional practices that focus on end-stage surgical outcomes and advocates for a proactive, int...

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Medizinische Forschungstrends

Rheumatologie5 Artikel

Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review).

Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review).

NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome.

Erythrocyte patch for enhanced B cell depletion therapy.

Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.

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