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Medizinische Forschungstrends

Die wirkungsvollsten Publikationen der Woche in 29 Fachgebieten, KI-kuratiert

Zuletzt aktualisiert: 11. Mai 2026

Hämatologie5 Artikel

Impact 2

The prognostic value of AQP1 in hyperbilirubinemia related to ABO hemolytic disease of the newborn.

Veröffentlicht: 2026-12-31

Hematology (Amsterdam, Netherlands)

MediLens Indexiert: 2026-05-11

This study evaluates the prognostic value of Aquaporin 1 (AQP1) in neonates with ABO hemolytic disease of the newborn (ABO-HDN) and hyperbilirubinemia. A cohort of 168 neonates was analyzed, revealing that AQP1 levels were significantly elevated in affected infants compared to controls. The findi...

Auf PubMed lesen
Impact 3

DOCK1 inhibitor Box5 (TFA) suppresses proliferation of AML cell lines and prolongs survival in AML xenograft models.

Veröffentlicht: 2026-05-11

Scientific reports

MediLens Indexiert: 2026-05-12

This study investigates the role of DOCK1 in acute myeloid leukemia (AML), identifying it as a prognostic biomarker with elevated expression predicting poor survival. The research demonstrates that targeting DOCK1 through a novel small-molecule inhibitor, Box5 (TFA), significantly reduces AML cel...

Auf PubMed lesen
Impact 3

Preliminary investigation into the association of serum free kappa light chains with risk stratification, clonal evolution and precision therapy in multiple myeloma.

Veröffentlicht: 2026-05-11

British journal of haematology

MediLens Indexiert: 2026-05-12

This study highlights the clinical significance of abnormal serum free light chain (sFLC) κ in newly diagnosed multiple myeloma (NDMM). A retrospective analysis of 113 NDMM patients revealed that abnormal sFLC κ is associated with poor prognosis and lower rates of deep remission following VRd the...

Auf PubMed lesen
Impact 2

Impact of Tranexamic acid in reducing intra-operative blood loss during mono-polar TURP in geriatric population: a comparative study from Pakistan - a state highly prevalent of anemia.

Veröffentlicht: 2026-05-11

BMC urology

MediLens Indexiert: 2026-05-12

In a study involving 60 elderly patients undergoing Transurethral Resection of the Prostate (TURP), the administration of a single 1 g dose of tranexamic acid (TXA) before anesthesia significantly reduced intra-operative blood loss compared to a control group. Blood loss was 289 ± 76 ml in the TX...

Auf PubMed lesen
Impact 2

Management of Iron Overload in Infants and Toddlers With Diamond-Blackfan Anemia Syndrome: A French-Italian Study.

Veröffentlicht: 2026-05-11

American journal of hematology

MediLens Indexiert: 2026-05-12

This study investigates the management of iron overload in young patients with Diamond-Blackfan Anemia Syndrome (DBAS) requiring chronic transfusions. A retrospective analysis of 167 patients revealed that 38% began chelation therapy before age three, primarily using deferasirox. The therapy sign...

Auf PubMed lesen

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